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Sibship T(2 )association tests of complex diseases for tightly linked markers

For population case-control association studies, the false-positive rates can be high due to inappropriate controls, which can occur if there is population admixture or stratification. Moreover, it is not always clear how to choose appropriate controls. Alternatively, the parents or normal sibs can...

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Autori principali: Fan, Ruzong, Knapp, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530186/
https://ncbi.nlm.nih.gov/pubmed/16004725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-7364-2-2-90
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