Impaired mitochondrial respiration and decreased fatigue resistance followed by severe muscle weakness in skeletal muscle of mitochondrial DNA mutator mice

Mitochondrial dysfunction can drastically impair muscle function, with weakness and exercise intolerance as key symptoms. Here we examine the time course of development of muscle dysfunction in a mouse model of premature ageing induced by defective proofreading function of mitochondrial DNA (mtDNA)...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yamada, Takashi, Ivarsson, Niklas, Hernández, Andrés, Fahlström, Andreas, Cheng, Arthur J, Zhang, Shi-Jin, Bruton, Joseph D, Ulfhake, Brun, Westerblad, Håkan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Skeletal Muscle and Exercise
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530125/
https://ncbi.nlm.nih.gov/pubmed/22988144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.240077
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados