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Decreased microRNA(miR)-145 and increased miR-224 expression in T cells from patients with systemic lupus erythematosus involved in lupus immunopathogenesis

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with abnormal T cell immune responses. We hypothesized that aberrant expression of microRNAs (miRNAs) in T cells may contribute to the pathogenesis of SLE. First, we analysed the expression profiles of 270 human miRNAs in T cells fr...

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Detalhes bibliográficos
Main Authors: Lu, M-C, Lai, N-S, Chen, H-C, Yu, H-C, Huang, K-Y, Tung, C-H, Huang, H-B, Yu, C-L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530100/
https://ncbi.nlm.nih.gov/pubmed/23199328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2012.04676.x
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