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HIV Pathogenesis: Dynamics and Genetics of Viral Populations and Infected Cells

In the absence of treatment, HIV-1 infection, usually starting with a single virion, leads inexorably to a catastrophic decline in the numbers of CD4(+) T cells and to AIDS, characterized by numerous opportunistic infections as well as other symptoms, including dementia and wasting. In the 30 years...

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Detalles Bibliográficos
Main Authors: Coffin, John, Swanstrom, Ronald
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530041/
https://ncbi.nlm.nih.gov/pubmed/23284080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a012526
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