Delayed-Type Hypersensitivity to Sand Fly Saliva in Humans from a Leishmaniasis-Endemic Area of Mali Is T(H)1-Mediated and Persists to Midlife

Immunity to sand fly saliva in rodents induces a T(H)1 delayed-type hypersensitivity (DTH) response conferring protection against leishmaniasis. The relevance of DTH to sand fly bites in humans living in a leishmaniasis-endemic area remains unknown. Here, we describe the duration and nature of DTH t...

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Detalhes bibliográficos
Main Authors: Oliveira, Fabiano, Traoré, Bourama, Gomes, Regis, Faye, Ousmane, Gilmore, Dana C, Keita, Somita, Traoré, Pierre, Teixeira, Clarissa, Coulibaly, Cheick A, Samake, Sibiry, Meneses, Claudio, Sissoko, Ibrahim, Fairhurst, Rick M, Fay, Michael P, Anderson, Jennifer M, Doumbia, Seydou, Kamhawi, Shaden, Valenzuela, Jesus G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529997/
https://ncbi.nlm.nih.gov/pubmed/22992802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.315
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