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In vivo measurement of CBF using (17)O NMR signal of metabolically produced H(2)(17)O as a perfusion tracer

The cerebral metabolic rate of oxygen (CMRO(2)) of small animals can be reliably imaged using the in vivo (17)O MR approach at high field. However, a separate measurement is required for imaging the cerebral blood flow (CBF) in the same animal. In this study, we demonstrate that the (17)O NMR signal...

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Detalhes bibliográficos
Main Authors: Zhu, Xiao-Hong, Zhang, Yi, Wiesner, Hannes, Ugurbil, Kamil, Chen, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529985/
https://ncbi.nlm.nih.gov/pubmed/23001743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.24469
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