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Anti-herpes simplex virus and anti-human cell growth activity of E-5-propenyl-2'-deoxyuridine and the concept of selective protection in antivirus chemotherapy.

E-5-Propenyl-2'-deoxyuridine (E-5-propenyl-dUrd) inhibited the growth of herpes simplex virus (HSV) types 1 (HSV-1) and 2 in culture. The concentration of drug required to give a 2-log reduction in virus titer was 5 microM for HSV-1 and 23 microM for HSV-2. The anti-HSV-1 activity of this agent...

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Dettagli Bibliografici
Autori principali: Cheng, Y C, Grill, S, Ruth, J, Bergstrom, D E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1980
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC352997/
https://ncbi.nlm.nih.gov/pubmed/6263181
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