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Early rise in circulating endothelial protein C receptor correlates with poor outcome in severe sepsis

PURPOSE: The endothelial protein C receptor (EPCR) negatively regulates the coagulopathy and inflammatory response in sepsis. Mechanisms controlling the expression of cell-bound and circulating soluble (s)EPCR are still unclear. Moreover, the clinical impact of EPCR shedding and its potential value...

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Detalhes bibliográficos
Main Authors: Guitton, Christophe, Gérard, Nathalie, Sébille, Véronique, Bretonnière, Cédric, Zambon, Olivier, Villers, Daniel, Charreau, Béatrice
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Verlag 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529933/
https://ncbi.nlm.nih.gov/pubmed/21394629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-011-2171-y
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