Smoking, variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma: a pooled analysis within the InterLymph consortium

PURPOSE: Studies of smoking and risk of non-Hodgkin lymphoma (NHL) have yielded inconsistent results, possibly due to subtype heterogeneity and/or genetic variation impacting the metabolism of tobacco-derived carcinogens, including substrates of the N-acetyltransferase enzymes NAT1 and NAT2. METHODS...

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Main Authors: Gibson, Todd M., Smedby, Karin E., Skibola, Christine F., Hein, David W., Slager, Susan L., de Sanjosé, Silvia, Vajdic, Claire M., Zhang, Yawei, Chiu, Brian C.-H., Wang, Sophia S., Hjalgrim, Henrik, Nieters, Alexandra, Bracci, Paige M., Kricker, Anne, Zheng, Tongzhang, Kolar, Carol, Cerhan, James R., Darabi, Hatef, Becker, Nikolaus, Conde, Lucia, Holford, Theodore R., Weisenburger, Dennis D., De Roos, Anneclaire J., Butterbach, Katja, Riby, Jacques, Cozen, Wendy, Benavente, Yolanda, Palmers, Casey, Holly, Elizabeth A., Sampson, Joshua N., Rothman, Nathaniel, Armstrong, Bruce K., Morton, Lindsay M.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529854/
https://ncbi.nlm.nih.gov/pubmed/23160945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-012-0098-4
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