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Complex modulation of the expression of PKC isoforms in the rat brain during chronic type 1 diabetes mellitus

We previously demonstrated that chronic hyperglycemia has a detrimental influence on neurovascular coupling in the brain—an effect linked to an alteration in the protein kinase C (PKC)-mediated phosphorylation pattern. Moreover, the activity of PKC was increased, in diabetic rat brain, in a tissue f...

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Hlavní autoři: Vetri, Francesco, Chavez, Rafael, Xu, Hao-Liang, Paisansathan, Chanannait, Pelligrino, Dale A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529837/
https://ncbi.nlm.nih.gov/pubmed/23103504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.10.032
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