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Enzymatic discovery of a HER-2/neu epitope that generates cross-reactive T cells

Patients with HER-2/neu-expressing breast cancer remain at risk for relapse following standard therapy. Vaccines targeting HER-2/neu to prevent relapse are in various phases of clinical testing. Many vaccines incorporate the HER-2/neu HLA-A2 binding peptide p369–377 (KIFGSLAFL), since it has been sh...

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Detalhes bibliográficos
Main Authors: Henle, Andrea M., Erskine, Courtney L., Benson, Linda M., Clynes, Raphael, Knutson, Keith L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529812/
https://ncbi.nlm.nih.gov/pubmed/23180824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201264
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