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Brain and Testicular Tumors in Mice with Progenitor Cells Lacking BAX and BAK
The pro-apoptotic BCL-2 family proteins BAX and BAK serve as essential gatekeepers of the intrinsic apoptotic pathway and, when activated, transform into pore forming homo-oligomers that permeabilize the mitochondrial outer membrane. Deletion of Bax and Bak causes marked resistance to death stimuli...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529761/ https://ncbi.nlm.nih.gov/pubmed/22986529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.421 |
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