Natural Antibodies in Normal Human Serum Inhibit Staphylococcus aureus Capsular Polysaccharide Vaccine Efficacy

Background. Vaccines against Streptococcus pneumoniae, Neisseria meningitidis, and Hemophilus influenzae type b induce functional opsonic or bactericidal antibodies to surface capsular polysaccharides (CP). Targeting the comparable Staphylococcus aureus CP seems logical, but to date such efforts hav...

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Main Authors: Skurnik, David, Kropec, Andrea, Roux, Damien, Theilacker, Christian, Huebner, Johannes, Pier, Gerald B.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529611/
https://ncbi.nlm.nih.gov/pubmed/22806596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cis624
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