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Mitotic spindle (DIS)orientation and DISease: Cause or consequence?

Correct alignment of the mitotic spindle during cell division is crucial for cell fate determination, tissue organization, and development. Mutations causing brain diseases and cancer in humans and mice have been associated with spindle orientation defects. These defects are thought to lead to an im...

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Detalhes bibliográficos
Main Authors: Noatynska, Anna, Gotta, Monica, Meraldi, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529530/
https://ncbi.nlm.nih.gov/pubmed/23266953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201209015
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