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The Use of Silica Coated MnO Nanoparticles to Control MRI Relaxivity in Response to Specific Physiological Changes

MnO nanoparticles have been tested to engineer a delayed increase in MRI T(1) relaxivity caused by cellular uptake via endocytosis into acidic compartments. Various coatings on core-shell structured MnO nanoparticles were tested for those that had the lowest T(1) relaxivity at pH 7.4, a pH where MnO...

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Detalhes bibliográficos
Main Authors: Lee, Yi-Cheng, Chen, Der-Yow, Dodd, Stephen J., Bouraoud, Nadia, Koretsky, Alan P., Krishnan, Kannan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529474/
https://ncbi.nlm.nih.gov/pubmed/22341582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.01.062
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