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APOLIPOPROTEIN E (APOE) INDUCES ANTI-INFLAMMATORY PHENOTYPE IN MACROPHAGES

OBJECTIVES: Apolipoprotein E (apoE) exerts potent anti-inflammatory effects. We here investigated the effect of apoE on the functional phenotype of macrophages. METHODS AND RESULTS: Human apoE receptors VLDL-R or apoER2 were stably expressed in RAW264.7 mouse macrophages. In these cells apoE downreg...

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Hlavní autoři: Baitsch, Daniel, Bock, Hans H., Engel, Thomas, Telgmann, Ralph, Müller-Tidow, Carsten, Varga, Georg, Bot, Martine, Herz, Joachim, Robenek, Horst, von Eckardstein, Arnold, Nofer, Jerzy-Roch
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529398/
https://ncbi.nlm.nih.gov/pubmed/21350196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.222745
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