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Glafenine-induced intestinal injury in zebrafish is ameliorated by μ-opioid signaling via enhancement of Atf6-dependent cellular stress responses

Beside their analgesic properties, opiates exert beneficial effects on the intestinal wound healing response. In this study, we investigated the role of μ-opioid receptor (MOR) signaling on the unfolded protein response (UPR) using a novel zebrafish model of NSAID-induced intestinal injury. The NSAI...

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Hlavní autoři: Goldsmith, Jason R., Cocchiaro, Jordan L., Rawls, John F., Jobin, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Limited 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529347/
https://ncbi.nlm.nih.gov/pubmed/22917923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.009852
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