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Mutation of sec63 in zebrafish causes defects in myelinated axons and liver pathology
Mutations in SEC63 cause polycystic liver disease in humans. Sec63 is a member of the endoplasmic reticulum (ER) translocon machinery, although it is unclear how mutations in SEC63 lead to liver cyst formation in humans. Here, we report the identification and characterization of a zebrafish sec63 mu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Limited
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529346/ https://ncbi.nlm.nih.gov/pubmed/22864019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.009217 |
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