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Closed-loop neural stimulation for pentylenetetrazole-induced seizures in zebrafish

Neural stimulation can reduce the frequency of seizures in persons with epilepsy, but rates of seizure-free outcome are low. Vagus nerve stimulation prevents seizures by continuously activating noradrenergic projections from the brainstem to the cortex. Cortical norepinephrine then increases GABAerg...

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Bibliographic Details
Main Authors: Pineda, Ricardo, Beattie, Christine E., Hall, Charles W.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Limited 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529339/
https://ncbi.nlm.nih.gov/pubmed/22822044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.009423
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