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Mezlocillin pharmacokinetics in patients with normal and impaired renal functions.

The pharmacokinetics of intravenous bolus doses of 1.0 g of mezlocillin were studied in 13 persons with normal and reduced renal functions. In renal failure a moderate increase was observed for the terminal serum half-life(t1/2 beta). This changed from a mean of 1.1 h at a glomerular filtration rate...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Bergan, T, Brodwall, E K, Wiik-Larsen, E
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1979
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352923/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/526008/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.16.5.651
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