Glutathione peroxidase overexpression causes aberrant ERK activation in neonatal mouse cortex after hypoxic preconditioning

BACKGROUND: Preconditioning of neonatal mice with nonlethal hypoxia (HPC) protects the brain from hypoxic–ischemic (HI) injury. Overexpression of human glutathione peroxidase 1 (GPx1), which normally protects the developing murine brain from HI injury, reverses HPC protection, suggesting that a cert...

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Detalhes bibliográficos
Main Authors: Autheman, Delphine, Sheldon, R. Ann, Chaudhuri, Nondini, von Arx, Sebastian, Siegenthaler, Corinne, Ferriero, Donna M., Christen, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529181/
https://ncbi.nlm.nih.gov/pubmed/23007029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2012.124
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