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Early embryonic priming of a miRNA locus predetermines postmitotic neuronal left-right asymmetry in C. elegans
The mechanisms by which functional left/right asymmetry arises in morphologically symmetric nervous systems are poorly understood. Here we provide a mechanistic framework for how functional asymmetry in a postmitotic neuron pair is specified in C. elegans. A key feature of this mechanism is a tempor...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529140/ https://ncbi.nlm.nih.gov/pubmed/23201143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.10.049 |
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