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F-actin buckling coordinates contractility and severing in a biomimetic actomyosin cortex

Here we develop a minimal model of the cell actomyosin cortex by forming a quasi-2D cross-linked filamentous actin (F-actin) network adhered to a model cell membrane and contracted by myosin thick filaments. Myosin motors generate both compressive and tensile stresses on F-actin and consequently ind...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Murrell, Michael P., Gardel, Margaret L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529094/
https://ncbi.nlm.nih.gov/pubmed/23213249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214753109
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