How nature can exploit nonspecific catalytic and carbohydrate binding modules to create enzymatic specificity

Noncatalytic carbohydrate binding modules (CBMs) are components of glycoside hydrolases that attack generally inaccessible substrates. CBMs mediate a two- to fivefold elevation in the activity of endo-acting enzymes, likely through increasing the concentration of the appended enzymes in the vicinity...

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Detalhes bibliográficos
Main Authors: Cuskin, Fiona, Flint, James E., Gloster, Tracey M., Morland, Carl, Baslé, Arnaud, Henrissat, Bernard, Coutinho, Pedro M., Strazzulli, Andrea, Solovyova, Alexandra S., Davies, Gideon J., Gilbert, Harry J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529030/
https://ncbi.nlm.nih.gov/pubmed/23213210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212034109
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