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Possible role of pineal allopregnanolone in Purkinje cell survival

It is believed that neurosteroids are produced in the brain and other nervous systems. Here, we show that allopregnanolone (ALLO), a neurosteroid, is exceedingly produced in the pineal gland compared with the brain and that pineal ALLO acts on the Purkinje cell, a principal cerebellar neuron, to pre...

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Auteurs principaux: Haraguchi, Shogo, Hara, Sakurako, Ubuka, Takayoshi, Mita, Masatoshi, Tsutsui, Kazuyoshi
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529028/
https://ncbi.nlm.nih.gov/pubmed/23213208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210804109
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