Zinc induces long-term upregulation of T-type calcium current in hippocampal neurons in vivo

Extracellular zinc can induce numerous acute and persistent physiological and toxic effects in neurons by acting at their plasma membrane or intracellularly following permeation or uptake into them. Zinc acutely and reversibly blocks T-type voltage-gated calcium current (I(CaT)), but the long-term e...

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Hlavní autoři: Ekstein, Dana, Benninger, Felix, Daninos, Moshe, Pitsch, Julika, van Loo, Karen M J, Becker, Albert J, Yaari, Yoel
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2012
Témata:
Neuroscience: Neurobiology of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528998/
https://ncbi.nlm.nih.gov/pubmed/22930274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.242537
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