Deletion of Chromosomes 13q and 14q Is a Common Feature of Tumors with BRCA2 Mutations

INTRODUCTION: Germline BRCA1 or BRCA2 mutations account for 20–30% of familial clustering of breast cancer. The main indication for BRCA2 screening is currently the family history but the yield of mutations identified in patients selected this way is low. METHODS: To develop more efficient approache...

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Main Authors: Rouault, Audrey, Banneau, Guillaume, MacGrogan, Gaëtan, Jones, Natalie, Elarouci, Nabila, Barouk-Simonet, Emmanuelle, Venat, Laurence, Coupier, Isabelle, Letouzé, Eric, de Reyniès, Aurélien, Bonnet, Françoise, Iggo, Richard, Sévenet, Nicolas, Longy, Michel
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528765/
https://ncbi.nlm.nih.gov/pubmed/23284877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052079
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