Selection and Characterization of a Candidate Therapeutic Bacteriophage That Lyses the Escherichia coli O104:H4 Strain from the 2011 Outbreak in Germany

In 2011, a novel strain of O104:H4 Escherichia coli caused a serious outbreak of foodborne hemolytic uremic syndrome and bloody diarrhea in Germany. Antibiotics were of questionable use and 54 deaths occurred. Candidate therapeutic bacteriophages that efficiently lyse the E. coli O104:H4 outbreak st...

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Autori principali: Merabishvili, Maia, De Vos, Daniel, Verbeken, Gilbert, Kropinski, Andrew M., Vandenheuvel, Dieter, Lavigne, Rob, Wattiau, Pierre, Mast, Jan, Ragimbeau, Catherine, Mossong, Joel, Scheres, Jacques, Chanishvili, Nina, Vaneechoutte, Mario, Pirnay, Jean-Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528706/
https://ncbi.nlm.nih.gov/pubmed/23285164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052709
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