Cubic regression-based degree of correction predicts the performance of whole bisulfitome amplified DNA methylation analysis

Epigenetic mechanisms, including DNA methylation, are important determinants in development and disease. There is a need for technologies capable of detecting small variations in methylation levels in an accurate and reproducible manner, even if only limited amounts of DNA are available (which is th...

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Autori principali: Fernandez-Jimenez, Nora, Plaza-Izurieta, Leticia, Lopez-Euba, Tamara, Jauregi-Miguel, Amaia, Ramon Bilbao, Jose
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
Soggetti:
Brief Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528690/
https://ncbi.nlm.nih.gov/pubmed/23154537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.22846
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