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Local treatment of a bone graft by soaking in zoledronic acid inhibits bone resorption and bone formation. A bone chamber study in rats

BACKGROUND: Bone grafts are frequently used in orthopaedic surgery. Graft remodelling is advantageous but can occur too quickly, and premature bone resorption might lead to decreased mechanical integrity of the graft. Bisphosphonates delay osteoclastic bone resorption but may also impair formation o...

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Detalhes bibliográficos
Main Authors: Belfrage, Ola, Isaksson, Hanna, Tägil, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528664/
https://ncbi.nlm.nih.gov/pubmed/23217097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-13-240
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