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Dihydrotestosterone induces SREBP-1 expression and lipogenesis through the phosphoinositide 3-kinase/Akt pathway in HaCaT cells

BACKGROUND: The purpose of this study was to investigate the effects and mechanisms of dihydrotestosterone (DHT)-induced expression of sterol regulatory element binding protein-1 (SREBP-1), and the synthesis and secretion of lipids, in HaCaT cells. HaCaT cells were treated with DHT and either the ph...

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Detalhes bibliográficos
Main Authors: Zhou, Bing-rong, Huang, Qiu-hong, Xu, Yang, Wu, Di, Yin, Zhi-qiang, Luo, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528431/
https://ncbi.nlm.nih.gov/pubmed/23153363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-11-156
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