A CXCL1 paracrine network links cancer chemoresistance and metastasis

Metastasis and chemoresistance in cancer are linked phenomena but the molecular basis for this link is unknown. We uncovered a network of paracrine signals between carcinoma, myeloid and endothelial cells that drives both processes in breast cancer. Cancer cells that overexpress CXCL1 and 2 by trans...

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Detalhes bibliográficos
Main Authors: Acharyya, Swarnali, Oskarsson, Thordur, Vanharanta, Sakari, Malladi, Srinivas, Kim, Juliet, Morris, Patrick G., Manova-Todorova, Katia, Leversha, Margaret, Hogg, Nancy, Seshan, Venkatraman E., Norton, Larry, Brogi, Edi, Massagué, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528019/
https://ncbi.nlm.nih.gov/pubmed/22770218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.04.042
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