Batch correction of microarray data substantially improves the identification of genes differentially expressed in Rheumatoid Arthritis and Osteoarthritis

BACKGROUND: Batch effects due to sample preparation or array variation (type, charge, and/or platform) may influence the results of microarray experiments and thus mask and/or confound true biological differences. Of the published approaches for batch correction, the algorithm “Combating Batch Effec...

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Bibliographic Details
Main Authors: Kupfer, Peter, Guthke, Reinhard, Pohlers, Dirk, Huber, Rene, Koczan, Dirk, Kinne, Raimund W
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528008/
https://ncbi.nlm.nih.gov/pubmed/22682473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-5-23
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