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Functional Analysis of Missense Mutations in Kv8.2 Causing Cone Dystrophy with Supernormal Rod Electroretinogram

Mutations in KCNV2 have been proposed as the molecular basis for cone dystrophy with supernormal rod electroretinogram. KCNV2 codes for the modulatory voltage-gated potassium channel α-subunit, Kv8.2, which is incapable of forming functional channels on its own. Functional heteromeric channels are h...

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Bibliografische gegevens
Hoofdauteurs: Smith, Katie E., Wilkie, Susan E., Tebbs-Warner, Joseph T., Jarvis, Bradley J., Gallasch, Linn, Stocker, Martin, Hunt, David M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527980/
https://ncbi.nlm.nih.gov/pubmed/23115240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.388033
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