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Localization and Substrate Selectivity of Sea Urchin Multidrug (MDR) Efflux Transporters

In this study, we cloned, expressed and functionally characterized Stronglycentrotus purpuratus (Sp) ATP-binding cassette (ABC) transporters. This screen identified three multidrug resistance (MDR) transporters with functional homology to the major types of MDR transporters found in humans. When ove...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gökirmak, Tufan, Campanale, Joseph P., Shipp, Lauren E., Moy, Gary W., Tao, Houchao, Hamdoun, Amro
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527970/
https://ncbi.nlm.nih.gov/pubmed/23124201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.424879
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