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Effect of 5-Iodo-5′-Amino-2′,5′-Dideoxyuridine on Varicella-Zoster Virus In Vitro

The antiviral effect of the nucleoside analog 5-iodo-5′-amino-2′,5′-dideoxyuridine (AIU) was tested with three isolates of varicella-zoster virus (VZV). AIU concentrations of 10 to 800 μM (3.5 to 288 μg/ml) reduced the number of plaques produced by VZV-infected cells and cell-free VZV from approxima...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Iltis, Jeffrey P., Lin, Tai-Shun, Prusoff, William H., Rapp, Fred
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1979
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352795/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/224809/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.16.1.92
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