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Human Fibroblast Interferon for Clinical Trials: Pharmacokinetics and Tolerability in Experimental Animals and Humans

Human fibroblast interferon (F-interferon) purified by adsorption on controlled-pore glass was given intramuscularly to patients at daily dosages of up to 20 × 10(6) units. Serum levels of antiviral activity were low or undetectable. In contrast, reasonably high serum titers were found in patients r...

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Detalhes bibliográficos
Main Authors: Billiau, Alfons, De Somer, Piet, Edy, Victor G., De Clercq, Erik, Heremans, Hubertine
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC352788/
https://ncbi.nlm.nih.gov/pubmed/475375
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