Human Fibroblast Interferon for Clinical Trials: Production, Partial Purification, and Characterization

The production and partial purification of human fibroblast interferon for performing clinical trials is described. The interferon was produced by superinduction (exposure to riboinosinic-ribocytidylic acid, cycloheximide, and actinomycin D) of large numbers of human diploid fibroblast cultures. The...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Billiau, Alfons, Van Damme, Jo, Van Leuven, Fred, Edy, Victor G., De Ley, Marc, Cassiman, Jean-Jacques, Van Den Berghe, Herman, De Somer, Piet
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1979
Soggetti:
Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352787/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/475374/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.16.1.49
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