Isolation and Properties of Metronidazole-Resistant Mutants of Bacteroides fragilis

Metronidazole-resistant mutants of Bacteroides fragilis, isolated after mutagenesis, had diminished ability to take up and metabolize the drug. All the metronidazole-resistant strains had depressed levels of pyruvate dehydrogenase compared with parent cultures. Their end products of glucose metaboli...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Britz, M. L., Wilkinson, R. G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1979
Assuntos:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352781/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/475371/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.16.1.19
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