The Utility of Mitochondrial and Y Chromosome Phylogenetic Data to Improve Correction for Population Stratification

Genome-wide association (GWA) studies have become a standard approach for discovering and validating genomic polymorphisms putatively associated with phenotypes of interest. Accounting for population structure in GWA studies is critical to attain unbiased parameter measurements and control Type I er...

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Detalhes bibliográficos
Main Authors: Makowsky, Robert, Yan, Qi, Wiener, Howard W., Sandel, Michael, Aissani, Brahim, Tiwari, Hemant K., Shrestha, Sadeep
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527715/
https://ncbi.nlm.nih.gov/pubmed/23267368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00301
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