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Exploration of the active site of Escherichia coli cystathionine γ-synthase
Cystathionine γ-synthase (CGS) catalyzes the condensation of O-succinyl-l-homoserine (l-OSHS) and l-cysteine (l-Cys), to produce l-cystathionine (l-Cth) and succinate, in the first step of the bacterial transsulfuration pathway. In the absence of l-Cys, the enzyme catalyzes the futile α,γ-eliminatio...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3527702/ https://ncbi.nlm.nih.gov/pubmed/22855027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2135 |
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