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Regulation of Amphiregulin Gene Expression by β-Catenin Signaling in Human Hepatocellular Carcinoma Cells: A Novel Crosstalk between FGF19 and the EGFR System

Hepatocellular carcinoma (HCC) is the most prevalent liver tumor and a deadly disease with limited therapeutic options. Dysregulation of cell signaling pathways is a common denominator in tumorigenesis, including hepatocarcinogenesis. The epidermal growth factor receptor (EGFR) signaling system is c...

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Bibliographic Details
Main Authors: Latasa, Maria U., Salis, Fabiana, Urtasun, Raquel, Garcia-Irigoyen, Oihane, Elizalde, Maria, Uriarte, Iker, Santamaria, Monica, Feo, Francesco, Pascale, Rosa M., Prieto, Jesús, Berasain, Carmen, Avila, Matías A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527604/
https://ncbi.nlm.nih.gov/pubmed/23285165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052711
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