Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells

Ovarian cancer is a highly lethal disease with poor prognosis and especially in high-grade tumor. Emerging evidence has reported that aberrant upregulation and activation of GRB7, ERK as well as FOXM1 are closely associated with aggresivenesss of human cancers. However, the interplay between these f...

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Autors principals: Chan, David W., Hui, Winnie W. Y., Cai, Patty C. H., Liu, Michelle X., Yung, Mingo M. H., Mak, Celia S. L., Leung, Thomas H. Y., Chan, Karen K. L., Ngan, Hextan Y. S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527599/
https://ncbi.nlm.nih.gov/pubmed/23285101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052578
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