Targeting GRB7/ERK/FOXM1 Signaling Pathway Impairs Aggressiveness of Ovarian Cancer Cells

Ovarian cancer is a highly lethal disease with poor prognosis and especially in high-grade tumor. Emerging evidence has reported that aberrant upregulation and activation of GRB7, ERK as well as FOXM1 are closely associated with aggresivenesss of human cancers. However, the interplay between these f...

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Главные авторы: Chan, David W., Hui, Winnie W. Y., Cai, Patty C. H., Liu, Michelle X., Yung, Mingo M. H., Mak, Celia S. L., Leung, Thomas H. Y., Chan, Karen K. L., Ngan, Hextan Y. S.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527599/
https://ncbi.nlm.nih.gov/pubmed/23285101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052578
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