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Negative Regulation of Pulmonary Th17 Responses by C3a Anaphylatoxin during Allergic Inflammation in Mice

Activation of complement is one of the earliest immune responses to exogenous threats, resulting in various cleavage products including anaphylatoxin C3a. In addition to its contribution to host defense, C3a has been shown to mediate Th2 responses in animal models of asthma. However, the role of C3a...

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Autores principales: Lim, Hoyong, Kim, Young Uk, Drouin, Scott M., Mueller-Ortiz, Stacey, Yun, Kyoungah, Morschl, Eva, Wetsel, Rick A., Chung, Yeonseok
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527591/
https://ncbi.nlm.nih.gov/pubmed/23285141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052666
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