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DNA Methylation in Multiple Myeloma Is Weakly Associated with Gene Transcription

Previous studies have now demonstrated that both genic and global hypomethylation characterizes the multiple myeloma (MM) epigenome. Whether these methylation changes are associated with global and corresponding increases (or decreases) in transcriptional activity are poorly understood. The purpose...

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Autori principali: Jung, Sungwon, Kim, Seungchan, Gale, Molly, Cherni, Irene, Fonseca, Rafael, Carpten, John, Salhia, Bodour
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527579/
https://ncbi.nlm.nih.gov/pubmed/23285118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052626
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