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N-glycosylation Dictates Proper Processing of Organic Anion Transporting Polypeptide 1B1

Organic anion transporting polypeptides (OATPs) have been extensively recognized as key determinants of absorption, distribution, metabolism and excretion (ADME) of various drugs, xenobiotics and toxins. Putative N-glycosylation sites located in the extracellular loops 2 and 5 is considered a common...

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Detalhes bibliográficos
Main Authors: Yao, Juan, Hong, Weifang, Huang, Jiujiu, Zhan, Kai, Huang, Hong, Hong, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527552/
https://ncbi.nlm.nih.gov/pubmed/23285087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052563
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