Vaccination with L. infantum chagasi Nucleosomal Histones Confers Protection against New World Cutaneous Leishmaniasis Caused by Leishmania braziliensis

BACKGROUND: Nucleosomal histones are intracellular proteins that are highly conserved among Leishmania species. After parasite destruction or spontaneous lysis, exposure to these proteins elicits a strong host immune response. In the present study, we analyzed the protective capability of Leishmania...

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Détails bibliographiques
Auteurs principaux: Carneiro, Marcia W., Santos, Diego M., Fukutani, Kiyoshi F., Clarencio, Jorge, Miranda, Jose Carlos, Brodskyn, Claudia, Barral, Aldina, Barral-Netto, Manoel, Soto, Manuel, de Oliveira, Camila I.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527524/
https://ncbi.nlm.nih.gov/pubmed/23284976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052296
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