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Salinomycin Inhibits Proliferation and Induces Apoptosis of Human Hepatocellular Carcinoma Cells In Vitro and In Vivo

The anti-tumor antibiotic salinomycin (Sal) was recently identified as a selective inhibitor of breast cancer stem cells; however, the effect of Sal on hepatocellular carcinoma (HCC) is not clear. This study aimed to determine the anti-tumor efficacy and mechanism of Sal on HCC. HCC cell lines (HepG...

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Autors principals: Wang, Fan, He, Lei, Dai, Wei-Qi, Xu, Ya-Ping, Wu, Dong, Lin, Chun-Lei, Wu, Shu-Mei, Cheng, Ping, Zhang, Yan, Shen, Miao, Wang, Chen-Feng, Lu, Jie, Zhou, Ying-Qun, Xu, Xuan-Fu, Xu, Ling, Guo, Chuan-Yong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527475/
https://ncbi.nlm.nih.gov/pubmed/23284640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050638
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