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Latent Herpes Simplex Virus Infections in Sensory Ganglia of Hairless Mice Prevented by Acycloguanosine

Acycloguanosine (ACG) was able to prevent the fatal outcome of herpes simplex virus-induced skin infections of the lumbosacral or orofacila area in hairless mice. Topical ACG treatment was more effective than systemic treatment in preventing the evolution of skin lesions. Acute ganglionic infections...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Klein, Richard J., Friedman-Kien, Alvin E., DeStefano, Eugene
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1979
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352744/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/230784/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.15.5.723
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