Selective Ablation of Ctip2/Bcl11b in Epidermal Keratinocytes Triggers Atopic Dermatitis-Like Skin Inflammatory Responses in Adult Mice

BACKGROUND: Ctip2 is crucial for epidermal homeostasis and protective barrier formation in developing mouse embryos. Selective ablation of Ctip2 in epidermis leads to increased transepidermal water loss (TEWL), impaired epidermal proliferation, terminal differentiation, as well as altered lipid comp...

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Hoofdauteurs: Wang, Zhixing, Zhang, Ling-juan, Guha, Gunjan, Li, Shan, Kyrylkova, Kateryna, Kioussi, Chrissa, Leid, Mark, Ganguli-Indra, Gitali, Indra, Arup K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527437/
https://ncbi.nlm.nih.gov/pubmed/23284675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051262
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